Date of Award

Fall 2021

Document Type



College of Natural and Health Sciences

Primary Advisor

Dr. Aimee Franklin


Multiple Sclerosis (MS) is an autoimmune, neuroinflammatory disorder that is characterized by the breakdown of myelinated axons in the Central and Peripheral Nervous Systems. It is a potentially debilitating autoimmune disease that affects almost 1 million people in the United States, and nearly 2.5 million people worldwide. The precise etiology of MS is still being researched, but much progress has been made towards understanding the molecular mechanisms and impactful ways to treat this disease. While there is still no cure, new treatment plans are constantly being orchestrated in effort to alleviate the burden that MS carries. Combination treatment plans have statistically proven to be the most beneficial in caring for the mind and body of MS patients. With new medications such as Larazotide, which aims to control leaky junctions, and dietary systems like the Paleolithic diet, that seeks to reduce saturated fat intake and inflammatory progenitors, the outlook for symptom management of MS is positive.